Download Files:
Products Details
Product Description
– RapaBlock is a potent, non-immunosuppressive and brain-impermeable FKBP12 ligand[1].
Web ID
– HY-153806
Shipping
– Room temperature
Molecular Formula
– C49H74N2O13
References
– [1]Ziyang Zhang, et al. Brain-restricted mTOR inhibition with binary pharmacology. Nature. 2022 Sep;609(7928):822-828.
CAS Number
– 2474076-02-1
Molecular Weight
– 899.12
SMILES
– O[C@H]1[C@H](OC)C[C@@](/C=C([C@H]([C@@H]([C@@H](O)CC([C@@H](/C=C(C)/C[C@@H](C[C@H](OC)[C@]2([H])[C@@H](OC)C[C@@H](C)[C@](O)(C3=O)O2)C)CCCC4=CC=CC=[N+]4[O-])=O)C)OC([C@@]5([H])N(C3=O)CCCC5)=O)C)([H])CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FKBP
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
