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Products Details
Product Description
– Ramiprilat-d5 is deuterium labeled Ramiprilat. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].
Web ID
– HY-A0115S1
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H23D5N2O5
References
– [1]Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active <b>angiotensin converting enzyme (ACE)</b> inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research<sup>[1]</sup>.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 2021255-43-4
Molecular Weight
– 393.49
SMILES
– O=C([C@@H]1C[C@@](CCC2)([H])[C@@]2([H])N1C([C@H](C)N[C@H](C(O)=O)CCC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Angiotensin-converting Enzyme (ACE);Endogenous Metabolite;Isotope-Labeled Compounds
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
