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Ramelteon metabolite M-II
SKU
HY-103005-Get quote
Category Reference compound
Tags Drug Metabolite;Melatonin Receptor, GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling, Neurological Disease; Endocrinology
Products Details
Product Description
– Ramelteon metabolite M-II is the major metabolite of Ramelteon, with IC50s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2). Ramelteon is a selective melatonin agonist.
Web ID
– HY-103005
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C16H21NO3
References
– [1]Nishiyama K, et al. Pharmacological characterization of M-II, the major human metabolite of ramelteon. Pharmacology. 2014;93(3-4):197-201.
CAS Number
– 896736-21-3
Molecular Weight
– 275.34
SMILES
– CC(O)C(NCC[C@@H]1CCC2=CC=C3OCCC3=C12)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Melatonin Receptor
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
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