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Ramelteon metabolite M-II

Products Details

Product Description

– Ramelteon metabolite M-II is the major metabolite of Ramelteon, with IC50s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2). Ramelteon is a selective melatonin agonist.

Web ID

– HY-103005

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C16H21NO3

References

– [1]Nishiyama K, et al. Pharmacological characterization of M-II, the major human metabolite of ramelteon. Pharmacology. 2014;93(3-4):197-201.

CAS Number

– 896736-21-3

Molecular Weight

– 275.34

SMILES

– CC(O)C(NCC[C@@H]1CCC2=CC=C3OCCC3=C12)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease; Endocrinology

Solubility

– 10 mM in DMSO

Target

– Drug Metabolite;Melatonin Receptor

Pathway

– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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