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Raloxifene-d4 (hydrochloride)
SKU
HY-13738S2-1 mg
Category Isotope-Labeled Compounds
Tags Cancer, Estrogen Receptor/ERR;Isotope-Labeled Compounds, Others;Vitamin D Related/Nuclear Receptor
Products Details
Product Description
– Raloxifene-d4 (hydrochloride) is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1].
Web ID
– HY-13738S2
Shipping
– Room temperature
Molecular Formula
– C28H24D4ClNO4S
References
– [1]Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439.|[2]Xu H, et al. Effect of caffeine on ovariectomy-induced osteoporosis in rats. Biomed Pharmacother. 2019;112:108650.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1188263-47-9
Molecular Weight
– 514.07
SMILES
– O=C(C1=CC=C(C=C1)OC([2H])([2H])C([2H])([2H])N2CCCCC2)C3=C(C4=CC=C(C=C4)O)SC5=CC(O)=CC=C53.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR;Isotope-Labeled Compounds
Pathway
– Others;Vitamin D Related/Nuclear Receptor
Product type
– Isotope-Labeled Compounds
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