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Products Details
Product Description
– Radotinib-d6 is deuterium labeled Radotinib.
Web ID
– HY-15728S
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H15D6F3N8O
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Kim SH, et al. Efficacy and safety of radotinib in chronic phase chronic myeloid leukemia patients with resistance or intolerance to BCR-ABL1 tyrosine kinase inhibitors. Haematologica. 2014 Jul;99(7):1191-6.
CAS Number
– 2754051-83-5
Molecular Weight
– 536.54
SMILES
– O=C(NC1=CC(C(F)(F)F)=CC(N2C=C(C)N=C2)=C1)C3=C([2H])C([2H])=C(C([2H])([2H])[2H])C(NC4=NC=CC(C5=NC=CN=C5)=N4)=C3[2H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcr-Abl;Isotope-Labeled Compounds
Pathway
– Others;Protein Tyrosine Kinase/RTK
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
