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Products Details
Product Description
– RAD51-IN-8, a new RAD51 binder, is a RAD51-BRCA2 inhibitor that inhibits the RAD51 BRCA2 protein protein interaction. RAD51-IN-8 also is a protein−protein interaction (PPI) inhibitor. RAD51-IN-8 has inhibitory activity for H4A4 with an EC50 value of 19 μM[1].
Web ID
– HY-150958
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H14Cl2FN3O2
References
– [1]Greta Bagnolini, et al. Identification of RAD51–BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry. ACS Med. Chem. Lett. 2022.
Molecular Weight
– 370.21
SMILES
– O=C(N/N=C/C1=CC=CN=C1F)CCCOC2=CC=C(Cl)C=C2Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RAD51
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
