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(Rac)-Timolol-d5 (maleate)
$950
Only 1000 item(s) left in stock.
Products Details
Product Description
– rac Timolol-d5 (maleate) is a labelled racemic (S)-Timolol maleate. (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction[1][2][3].
Web ID
– HY-17494S
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H23D5N4O7S
References
– [1]Mitrović M, et al. Analytical quality by design development of an ecologically acceptable enantioselective HPLC method for timolol maleate enantiomeric purity testing on ovomucoid chiral stationary phase. J Pharm Biomed Anal. 2020 Feb 20;180:113034.|[2]Wedian F, et al. Simultaneous spectrofluorometric analysis of tablets containing hydrochlorothiazide combined with timolol maleate or amiloride hydrochloride. Acta Pharm. 2020 Sep 1;70(3):373-385.|[3]Sun L, et al. Fractional 2940-nm Er:YAG Laser-Assisted Drug Delivery of Timolol Maleate for the Treatment of Deep Infantile Hemangioma. J Dermatolog Treat. 2020 Feb 11:1-24.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1217260-21-3
Molecular Weight
– 437.52
Compound Purity
– 99.0
SMILES
– C(=CC(O)=O)C(O)=O.O(C(C(C(NC(C)(C)C)([2H])[2H])(O)[2H])([2H])[2H])C=1C(=NSN1)N2CCOCC2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;Isotope-Labeled Compounds
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
