Download Files:
Products Details
Product Description
– (Rac)-MTK458 (compound 16) is an activator of mitophagy. EP-0035985 is the isomer of EP-0035985[1].
Web ID
– HY-152943A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H15F3N4
References
– [1]De Roulet D, et al. Preparation of purinamines and pyrrolopyrimidinamines, compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease. World Intellectual Property Organization, WO2020206363 A1 2020-10-08.
CAS Number
– 2499962-44-4
Molecular Weight
– 332.32
SMILES
– FC(F)(C1=CC2=C(NC3C4=C(CCC3)C=CC=C4)N=CN=C2N1)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Mitophagy
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
