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Product Description
– (Rac)-Dalzanemdor ((Rac)-SAGE-718) is an isomer of Dalzanemdor (HY-147260). Dalzanemdor is an orally active and highly intrinsically active N-methyl-d-aspartate receptor (NMDAR)-positive allosteric modulator (PAM). Dalzanemdor can be used in the research of Huntington’s disease[1].
Web ID
– HY-147260B
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C27H43F3O2
References
– [1]Hill MD, et al. SAGE-718: A First-in-ClassN-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment. J Med Chem. 2022 Jul 14;65(13):9063-9075.
CAS Number
– 2216703-16-9
Molecular Weight
– 456.62
SMILES
– C[C@@]12[C@]3([H])[C@](CC=C1C[C@@](O)(CC2)C)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(C)(O)C(F)(F)F)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
