Download Files:
Products Details
Product Description
– (Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer’s disease[1].
Web ID
– HY-103537
Shipping
– Room temperature
Molecular Formula
– C29H29F4NO2
References
– [1]Peng H, et al. Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator. ACS Med Chem Lett. 2011 Aug 5;2(10):786-91.
CAS Number
– 1257395-14-4
Molecular Weight
– 499.54
SMILES
– OC(C(C)C(C=C1)=CC(C2=CC=C(C(F)(F)F)C=C2)=C1C(N3CCC(C)CC3)C4=CC=C(F)C=C4)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β;γ-secretase
Pathway
– Neuronal Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
