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(Rac)-Bedaquiline

SKU HY-14881B-1 mg Category Reference compound Tags Infection, Others

$144 – $643

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Products Details

Product Description

– (Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis[1][2].

Web ID

– HY-14881B

Shipping

– Room temperature

Molecular Formula

– C32H31BrN2O2

References

– [1]Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Jun;55(6):483-487. |[2]Sarathy JP, et al. TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug’s Uncoupler Activity. Antimicrob Agents Chemother. 2020 Jan 27;64(2):e01540-19.

CAS Number

– 654655-80-8

Molecular Weight

– 555.50

SMILES

– BrC1=CC=C(N=C(OC)C(C(C(CCN(C)C)(O)C2=CC=CC3=C2C=CC=C3)C4=CC=CC=C4)=C5)C5=C1

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Others

Pathway

– Others

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.