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Rabeprazole
$40 – $60
Products Details
Product Description
– Rabeprazole (LY307640) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].
Web ID
– HY-B0656
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H21N3O3S
Citations
– Nat Commun. 2023 Jul 14;14(1):4217.|Front Immunol. 2022 Jun 21;13:895869.
References
– [1]Mengli Gu, et al. Rabeprazole Exhibits Antiproliferative Effects on Human Gastric Cancer Cell Lines. Oncol Lett. 2014 Oct;8(4):1739-1744.|[2]Aly A M Shaalan, et al. Supplement With Calcium or Alendronate Suppresses Osteopenia Due to Long Term Rabeprazole Treatment in Female Mice: Influence on Bone TRAP and Osteopontin Levels. Front Pharmacol. 2020 May 13;11:583.|[3]Tara A Shea, et al. Identification of Proton-Pump Inhibitor Drugs That Inhibit <i>Trichomonas Vaginalis</i> Uridine Nucleoside Ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4.
CAS Number
– 117976-89-3
Molecular Weight
– 359.44
SMILES
– O=S(C1=NC2=CC=CC=C2N1)CC3=NC=CC(OCCCOC)=C3C
Clinical Information
– Launched
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Bacterial;Proton Pump
Pathway
– Anti-infection;Apoptosis;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
