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RA190
$156 – $1,104
Products Details
Product Description
– RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
Web ID
– HY-100739
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H23Cl5N2O2
References
– [1]Anchoori RK, et al. A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer. Cancer Cell. 2013 Dec 9;24(6):791-805.
CAS Number
– 1617495-03-0
Molecular Weight
– 596.76
Compound Purity
– 99.09
SMILES
– O=C1/C(CN(C([C@@H](N)CC2=CC=CC=C2)=O)C/C1=C/C3=CC=C(Cl)C(Cl)=C3)=CC4=CC=C(Cl)C(Cl)=C4.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Proteasome
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
