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Products Details
Product Description
– (R)-SKF 38393 ((±)-SKF-38393) hydrochloride is a potent and selective D1 dopamine receptor antagonist. (R)-SKF 38393 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channel[1].
Web ID
– HY-12520B
Shipping
– Room temperature
Molecular Formula
– C16H18ClNO2
References
– [1]Kuzhikandathil EV, et, al. Classic D1 dopamine receptor antagonist R-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (SCH23390) directly inhibits G protein-coupled inwardly rectifying potassium channels. Mol Pharmacol. 2002 Jul;62(1):119-26.
CAS Number
– 81702-42-3
Molecular Weight
– 291.77
SMILES
– OC1=C(C=C2[C@H](CNCCC2=C1)C3=CC=CC=C3)O.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor;Potassium Channel
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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