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Product Description
– (R)-OY-101 is an orally active and specific inhibitor of P-gp. (R)-OY-101 increases tumor sensitivity to anticancer agents. (R)-OY-101 has good activity in reversing tumor resistance and promoting apoptosis and can be used in cancer related research[1].
Web ID
– HY-149053B
Shipping
– Room temperature
Molecular Formula
– C27H31NO4
References
– [1]Zeng R, et al. Simplified Derivatives of Tetrandrine as Potent and Specific P-gp Inhibitors to Reverse Multidrug Resistance in Cancer Chemotherapy. J Med Chem. 2023 Mar 23;66(6):4086-4105.
CAS Number
– 23495-82-1
Molecular Weight
– 433.54
SMILES
– CN1[C@H](CC2=CC=C(OC)C(OCC3=CC=CC=C3)=C2)C4=C(C=C(OC)C(OC)=C4)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;P-glycoprotein
Pathway
– Apoptosis;Membrane Transporter/Ion Channel
Product type
– Reference compound
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