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(R)-BRD3731
$450 – $2,600
Products Details
Product Description
– (R)-BRD3731 is a GSK3 inhibitor extracted from patent US20160375006A1, compound example 273, has IC50s of 1.05 and 6.7 μM for GSK3β and GSK3α, respectively[1].
Web ID
– HY-124607
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H31N3O
References
– [1]Scolnick E, et, al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.
CAS Number
– 2056262-08-7
Molecular Weight
– 377.52
Compound Purity
– 98.22
SMILES
– O=C1C2=C(N=C3C([C@@]2(C)C4=CC=CC=C4)=C(CC(C)(C)C)NN3)CC(C)(C)C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 200 mg/mL (ultrasonic)
Target
– GSK-3
Isoform
– GSK-3α;GSK-3β
Pathway
– PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
