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R-BC154 (acetate)
SKU
HY-136214-Get quote
Category Reference compound
Tags Cancer; Inflammation/Immunology, Cytoskeleton, Integrin
Products Details
Product Description
– R-BC154 acetate is a selective fluorescent α9β1 integrin antagonist. R-BC154 acetate acts as a useful high affinity, activation dependent integrin probe, which can be used to investigate α9β1 and α4β1 integrin binding activity[1].
Web ID
– HY-136214
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C56H65N9O14S3
References
– [1]Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells. Org Biomol Chem. 2014 Feb 14;12(6):965-78.
Molecular Weight
– 1184.36
SMILES
– CCN(C1=CC2=[O+]C3=C(C=CC(N(CC)CC)=C3)C(C4=CC=C(S(=O)(NCC5=CN([C@H]6CN(S(=O)(C7=CC=CC=C7)=O)[C@H](C(N[C@H](C(O)=O)CC8=CC=C(ON9CCCC9)C=C8)=O)C6)N=N5)=O)C=C4S(=O)(O)=O)=C2C=C1)CC.CC([O-])=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Integrin
Isoform
– α9β1
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.