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R 80123
$80
Only 1000 item(s) left in stock.
Web ID
– HY-100615A
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H29N5O3
References
– [1]Vandeplassche GM et al. Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs. J Cardiovasc Pharmacol. 1992 May;19(5):714-22.
https://www.ncbi.nlm.nih.gov/pubmed/ 1381769|[2]Schneider J et al. Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties.
Naunyn Schmiedebergs Arch Pharmacol. 1992 Nov;346(5):563-72.|[3]Vandeplassche GM et al. Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs. J Cardiovasc Pharmacol. 1992 May;19(5):714-22.
CAS Number
– 133718-30-6
Molecular Weight
– 459.54
Compound Purity
– 98.0
SMILES
– O=C(N(C1CCCCC1)C)CO/N=C(C2=CC=CC=C2)C3=CC4=C(N=C(NC(C5)=O)N5C4)C=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
