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Product Description
– (R)-6′,7′-Dihydroxybergamottin ((R)-6′,7′-DHB) is a competitive inhibitor of human and rat CYP1A1 activity with Kis of 55 μM and 1.72 μM, respectively. (R)-6′,7′-Dihydroxybergamottin has the potential for cancer research[1].
Web ID
– HY-N2689
Shipping
– Room temperature
Molecular Formula
– C21H24O6
References
– [1]Rebeca Santes-Palacios, et al. Inhibition of human and rat CYP1A1 enzyme by grapefruit juice compounds. Toxicol Lett. 2016 Sep 6:258:267-275.
CAS Number
– 264234-05-1
Molecular Weight
– 372.41
SMILES
– O=C1C=CC2=C(OC/C=C(C)/CC[C@@H](O)C(C)(O)C)C3=C(OC=C3)C=C2O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
