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Products Details
Product Description
– Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum Sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum Sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1[1].
Web ID
– HY-149881
Shipping
– Room temperature
Molecular Formula
– C19H13F2NO3
References
– [1]Zhang P, et al. Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors. J Med Chem. 2023 Jul 13;66(13):8441-8463.
CAS Number
– 2925926-80-1
Molecular Weight
– 341.31
SMILES
– O=C(C(CNC(C1=CC=C(C=C1)F)=O)=C2C3=CC=C(C=C3)F)OC2=C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
