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Quisqualic acid
$55 – $165
Products Details
Product Description
– Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica[1][2].
Web ID
– HY-12597
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C5H7N3O5
References
– [1]H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.|[2]Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83.
CAS Number
– 52809-07-1
Molecular Weight
– 189.13
Compound Purity
– 98.0
SMILES
– O=C(O)[C@@H](N)CN(C(N1)=O)OC1=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– iGluR;mGluR
Isoform
– mGluR1;mGluR2;mGluR4
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
