Download Files:
Quinine (hydrobromide)
SKU
HY-B1751C-Get quote
Category Reference compound
Tags Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease, Cytochrome P450;Parasite;Potassium Channel, Infection
Products Details
Product Description
– Quinidine hydrobromide is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine hydrobromide is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine hydrobromide can be used for malaria research[1][2][3].
Web ID
– HY-B1751C
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H25BrN2O2
References
– [1]Kehl SJ, et al. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13.|[2]Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.
CAS Number
– 549-49-5
Molecular Weight
– 405.33
SMILES
– O[C@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@@]3([H])[N@](C[C@@H]4C=C)CC[C@H]4C3.[H]Br
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;Parasite;Potassium Channel
Isoform
– Plasmodium
Pathway
– Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.