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Pyrrolidinedithiocarbamate (ammonium)
$66 – $73
Products Details
Product Description
– Pyrrolidinedithiocarbamate ammonium (Ammonium pyrrolidinedithiocarbamate) is a selective and blood-brain barrier (BBB) permeable NF-κB inhibitor.
Web ID
– HY-18738
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C5H12N2S2
References
– [1]Németh ZH, et al. Pyrrolidinedithiocarbamate inhibits NF-kappaB activation and IL-8 production in intestinal epithelial cells. Immunol Lett. 2003 Jan 2;85(1):41-6.|[2]Qin JD, et al. Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury. Pharm Biol. 2014 Nov;52(11):1460-1466.
CAS Number
– 5108-96-3
Molecular Weight
– 164.29
Compound Purity
– 98.57
SMILES
– SC(N1CCCC1)=S.N
Clinical Information
– Phase 3
Research Area
– Inflammation/Immunology; Cancer
Solubility
– H2O : 50 mg/mL (ultrasonic)
Target
– NF-κB
Isoform
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
