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Pyridoxal phosphate-d5
$1,638
Only 1000 item(s) left in stock.
Products Details
Product Description
– Pyridoxal phosphate-d5 is the deuterium labeled Pyridoxal phosphate. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia[1][2].
Web ID
– HY-B1744S
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C8H5D5NO6P
References
– [1]Grin IR, et al. Inactivation of NEIL2 DNA glycosylase by pyridoxal phosphate reveals a loop important for substrate binding. Biochem Biophys Res Commun. 2010 Mar 26;394(1):100-5.|[2]Modak MJ. Pyridoxal 5′ phosphate: a selective inhibitor of oncornaviral DNA polymerases. Biochem Biophys Res Commun. 1976 Jul 12;71(1):180-7.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1246818-16-5
Molecular Weight
– 252.17
SMILES
– C(OP(=O)(O)O)(C=1C(C=O)=C(O)C(C([2H])([2H])[2H])=NC1)([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Isotope-Labeled Compounds;Reverse Transcriptase
Pathway
– Anti-infection;Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
