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Pyridaben-d13
$298
Only 1000 item(s) left in stock.
Products Details
Product Description
– Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
Web ID
– HY-B0817S
Shipping
– Room temperature
Molecular Formula
– C19H12D13ClN2OS
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Gomez C,et al. Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome. Front Biosci. 2007 Jan 1;12:1079-93. |[3]Namin HH, et al. Resistance to pyridaben in Canadian greenhouse populations of two-spotted spider mites, Tetranychus urticae (Koch). Pestic Biochem Physiol. 2020 Nov170:104677.
CAS Number
– 2468638-05-1
Molecular Weight
– 378.01
SMILES
– [2H]C([2H])([2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(C([2H])=C1[2H])=C([2H])C([2H])=C1CSC2=C(C(N(N=C2)C(C)(C)C)=O)Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
