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Products Details
Product Description
– Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene azide 3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Web ID
– HY-D1295
Shipping
– Room temperature
Molecular Formula
– C26H28N4O3
References
– [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.
CAS Number
– 2252168-06-0
Molecular Weight
– 444.53
SMILES
– O=C(NCCOCCOCCN=[N+]=[N-])CCCC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PROTAC Linkers
Isoform
– PEG Linkers
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
