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Pyrazinamide
$55 – $158
Products Details
Product Description
– Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
Web ID
– HY-B0271
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C5H5N3O
References
– [1]Y Zhang, et al. Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide. J Bacteriol. 1999 Apr;181(7):2044-9.|[2]Ying Zhang, et al. Mechanisms of Pyrazinamide Action and Resistance. Microbiol Spectr. 2014 Aug;2(4):MGM2-0023-2013.
CAS Number
– 98-96-4
Molecular Weight
– 123.11
Compound Purity
– 99.97
SMILES
– O=C(C1=NC=CN=C1)N
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : ≥ 50 mg/mL|H2O : 6.67 mg/mL (ultrasonic)
Target
– Antibiotic;Autophagy;Bacterial
Pathway
– Anti-infection;Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
