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Pyoluteorin
$240
Only 1000 item(s) left in stock.
Products Details
Product Description
– Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses plant diseases caused by this fungus[1]. Pyoluteorin induces human triple-negative breast cancer MDA-MB-231 cells apoptosis in vitro. Pyoluteorin can be used for the research of human triple-negative breast cancer[2].
Web ID
– HY-114979
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C11H7Cl2NO3
References
– [1]B Nowak-Thompson, et al. Characterization of the pyoluteorin biosynthetic gene cluster of <i>Pseudomonas fluorescens</i> Pf-5. J Bacteriol. 1999 Apr;181(7):2166-74.|[2]Ting Ding, et al. Pyoluteorin induces cell cycle arrest and apoptosis in human triple-negative breast cancer cells MDA-MB-231. J Pharm Pharmacol. 2020 Jul;72(7):969-978.
CAS Number
– 25683-07-2
Molecular Weight
– 272.08
Compound Purity
– 96.0
SMILES
– O=C(C1=C(C=CC=C1O)O)C2=CC(Cl)=C(N2)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis;Fungal
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
