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PSMA-IN-3
Products Details
Product Description
– PSMA-IN-3 (compound 17) is a novel high-affinity PSMA inhibitor with an IC50 value of 13 nM. PSMA-IN-3 is suitable for developing an 18F-labeled radioligand for PET imaging of PSMA in prostate cancer[1].
Web ID
– HY-149869
Shipping
– Room temperature
Molecular Formula
– C43H50FN7O15
References
– [1]Gade NR, et al. N-Alkyl Carbamoylimidazoles as Versatile Synthons for the Synthesis of Urea-Based PSMA Inhibitors. ACS Med Chem Lett. 2023 Jun 9;14(7):943-948.
Molecular Weight
– 923.89
SMILES
– FC1=CC=C(C=C1)/C=N/OCC(NCC(N[C@H](C(O)=O)CC2=CC=C(C=C2)OCC(N[C@H](C(NCCCC[C@H](NC(N[C@H](C(O)=O)CCC(O)=O)=O)C(O)=O)=O)CC3=CC=CC=C3)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PSMA
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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