Products Details

Product Description

– PSMA-IN-2 is an inhibitor of PSMA with a Ki value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λEM = 1088 nm, λex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice[1].

Web ID

– HY-149298

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C54H60N14O18S2

References

– [1]Wang X, et al. Design and Characterization of Squaramic Acid-Based Prostate-Specific Membrane Antigen Inhibitors for Prostate Cancer. J Med Chem. 2023 May 25;66(10):6889-6904.

CAS Number

– 2946600-14-0

Molecular Weight

– 1257.27

SMILES

– CN(C1=CC=C(C2=C3N=S=NC3=C(C4=NSN=C42)C5=CC=C(C=C5)N(C)CCC(NCCCC[C@H](NC(N[C@H](C(O)=O)CNC(C6=O)=C(C6=O)O)=O)C(O)=O)=O)C=C1)CCC(NCCCC[C@H](NC(N[C@H](C(O)=O)CNC(C7=O)=C(C7=O)O)=O)C(O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– PSMA

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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