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PSMA-IN-1
Products Details
Product Description
– PSMA-IN-1 (compound 23) is an inhibitor of PSMA with a Ki value of 2.49 nM. PSMA-IN-1 inhibits tumor growth with high selectivity and specificity in PSMA+ xenograft models. PSMA-IN-1 is a NIR probe (λEX: 620 nm; λEM: 670 nm) used for tumor disappearance. PSMA-IN-1 can be used for research on prostate cancer[1].
Web ID
– HY-149297
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C66H80N10O20
References
– [1]Wang X, et al. Design and Characterization of Squaramic Acid-Based Prostate-Specific Membrane Antigen Inhibitors for Prostate Cancer. J Med Chem. 2023 May 25;66(10):6889-6904.
Molecular Weight
– 1333.40
SMILES
– OC(C1=O)=C(NC[C@H](NC(N[C@@H](CCCCNC(CCCCC[N+]2=C(C(C)(C3=C2C=CC=C3)C)/C=C4C([O-])=C(C4=O)/C=C5C(C)(C6=C(N/5CCCCCC(NCCCC[C@H](NC(N[C@H](C(O)=O)CNC(C7=O)=C(C7=O)O)=O)C(O)=O)=O)C=CC=C6)C)=O)C(O)=O)=O)C(O)=O)C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PSMA
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.