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PSB36
$710 – $1,150
Products Details
Product Description
– PSB36 is a potent and selective antagonist of adenosine A1 receptor, with Kis 0.12 nM, 187 nM, 552 nM, 2300 nM, and 6500 nM for rA1, hA2B, rA2A, hA3 and rA3 receptors respectively. PSB36 can be used for the research of hyperalgesia[1][2].
Web ID
– HY-103175
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H30N4O3
References
– [1]Abo-Salem OM, et, al. Antinociceptive effects of novel A2B adenosine receptor antagonists. J Pharmacol Exp Ther. 2004 Jan;308(1):358-66.|[2]Bilkei-Gorzo A, et, al. Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia. Naunyn Schmiedebergs Arch Pharmacol. 2008 Mar;377(1):65-76.
CAS Number
– 524944-72-7
Molecular Weight
– 386.49
Compound Purity
– 99.0
SMILES
– O=C(N1CCCC)N(CCCO)C2=C(N=C(C34CC(C5)CC3CC5C4)N2)C1=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Target
– Adenosine Receptor
Isoform
– Adenosine A1 receptor (A1R);Adenosine A2A receptor (A2AR);Adenosine A2B receptor (A2BR);Adenosine A3 receptor (A3R)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
