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Protein kinase inhibitor 4
SKU
HY-153743-Get quote
Category Reference compound
Tags Cancer, Neuronal Signaling;Protein Tyrosine Kinase/RTK, ROS Kinase;Trk Receptor
Products Details
Product Description
– Protein kinase inhibitor 4 (Compound 3) is a protein kinase inhibitor that inhibits TRK-A and ROS1 (IC50=3.0 nM and 104 nM respectively)[1].
Web ID
– HY-153743
Shipping
– Room temperature
Molecular Formula
– C25H24F2N6O3S
References
– [1]Dawei Zhang, et al. Substituted pyrazolopyrimidines useful as kinases inhibitors. Patent. WO2019029629A1.
CAS Number
– 2278205-04-0
Molecular Weight
– 526.56
SMILES
– FC1=C(C=C(C=C1)F)[C@@H]2N(C3=NC4=C(C=NN4C=C3)NC(C5=CC=C(C=C5)NS(CC)(=O)=O)=O)CCC2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ROS Kinase;Trk Receptor
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.