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Products Details
Product Description
– Protein kinase D inhibitor 1 (compound 17m) is a pan-PKD inhibitor, with IC50 values ranging from 17 to 35 nM. Protein kinase D inhibitor 1 inhibits PKD-dependent cortactin phosphorylation[1].
Web ID
– HY-151372
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H21N7
References
– [1]Gilles P, et al. Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors. Eur J Med Chem. 2020 Nov 1;205:112638.
CAS Number
– 2489320-03-6
Molecular Weight
– 347.42
SMILES
– NC1=C2C(N(CC3CCNCC3)N=C2C4=CNC5=C4C=CC=C5)=NC=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PKD
Isoform
– PKD1;PKD2;PKD3
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
