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PROTAC KRAS G12C degrader-3
Products Details
Product Description
– PROTAC KRAS G12C degrader-3 (Comp 283) is a potent KRAS G12C degrader for cancer research[1].
Web ID
– HY-153881
Shipping
– Room temperature
Molecular Formula
– C63H75ClN14O6
References
– [1]Methods and compositions for targeted protein degradation.WO2022078414.
CAS Number
– 2768099-51-8
Molecular Weight
– 1159.81
SMILES
– O=C(C=C)N1CCN(C2=NC(OC[C@H]3N(C)C[C@@H](N4CCN(C(C5CCN(CC6=CC=C(N7C(C(NCC)=O)=NN=C7C8=C(O)C=C(O)C(C(C)C)=C8)C=C6)CC5)=O)CC4)C3)=NC9=C2CCN(C%10=C(C(Cl)=CC=C%11)C%11=CC=C%10)C9)C[C@@H]1CC#N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.