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PROTAC IRAK4 ligand-1
$400 – $2,200
Products Details
Product Description
– PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4 (IRAK4). PROTAC IRAK4 ligand-1 can be used in the synthesis of PROTAC IRAK4 degrader-1 (HY-129966)[1].
Web ID
– HY-129967
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H27F3N6O6
References
– [1]Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
CAS Number
– 2357108-39-3
Molecular Weight
– 612.56
Compound Purity
– 99.49
SMILES
– FC(F)(F)C1=NN(C=C1NC(C2=COC(C3=CC=NC(N(C(OC(C)(C)C)=O)CC4CC4)=C3)=N2)=O)C5=CC=C(C(O)=O)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Ligands for Target Protein for PROTAC
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
