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Products Details
Product Description
– PROTAC IRAK4 degrader-6 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-172[1].
Web ID
– HY-139317
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C42H41F3N12O8
References
– [1]https://scifinder-n.cas.org/patent-viewer?docuri=g__2-GF3YbbKfwweYAYLNnmYDIpK1sFeQGP9cmlPB_4&markedFullTextKey=GFB6kc_cFl60fBy8t-u8qupJE998gaydSFApjgE-p5c.pdf
CAS Number
– 2360530-72-7
Molecular Weight
– 898.85
SMILES
– O=C(C1=NN(C2=CC=C(C(NCCCCCNCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IRAK;PROTACs
Isoform
– IRAK4
Pathway
– Immunology/Inflammation;PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
