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Products Details
Product Description
– PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader extracted from patent US20190192668A1, compound I-171[1].
Web ID
– HY-139316
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C41H40F3N11O9
References
– [1]Mainolfi N, et, al. Irak degraders and uses thereof. US20190192668A1.
CAS Number
– 2360530-61-4
Molecular Weight
– 887.82
SMILES
– O=C(C1=NN(C2=CC=C(CNCCOCCOCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IRAK;PROTACs
Isoform
– IRAK4
Pathway
– Immunology/Inflammation;PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
