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PROTAC IRAK3 degrade-1 (formic)
$450 – $8,500
Products Details
Product Description
– PROTAC IRAK3 degrade-1 (compound 23) formic is a potent and selective degrader of IRAK3 (IC50=5 nM)[1].
Web ID
– HY-142662A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C48H65N11O8
References
– [1]Degorce SL, et al. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase. J Med Chem. 2020 Sep 24;63(18):10460-10473.
Molecular Weight
– 924.10
Compound Purity
– 98.10
SMILES
– O=C1C2=CC(N3CCN(CC3)CCC4CCN(CC4)C(CCC(N5CCN([C@@]6([H])CC[C@H](CC6)NC7=NC=NN8C7=C(C(C)C)C=C8)CC5)=O)=O)=CC=C2C(N1C9C(NC(CC9)=O)=O)=O.O=CO
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 150 mg/mL (ultrasonic)
Target
– PROTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
