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PROTAC ERRα Degrader-1
SKU
HY-128838-Get quote
Category Reference compound
Tags Cancer, Estrogen Receptor/ERR;PROTACs, PROTAC;Vitamin D Related/Nuclear Receptor
Products Details
Product Description
– PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an PROTAC estrogen-related receptor alpha (ERRa) degrader[1].
Web ID
– HY-128838
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C54H49Cl2F6N7O8
References
– [1]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
CAS Number
– 2306388-84-9
Molecular Weight
– 1108.91
SMILES
– O=C(N1CC(N(CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC3=C(C=C(C(F)(F)F)C=C3)C(F)(F)F)C=C2)=O)=O)CC1)=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C7=C(C=C(OC)C=C7)OC(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR;PROTACs
Isoform
– ERRα;MDM2
Pathway
– PROTAC;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.