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Products Details
Product Description
– PROTAC eDHFR Degrader-2 (compound 7b) is a potent degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), enabling robust degradation of eDHFR-tagged proteins[1].
Web ID
– HY-149679
Shipping
– Room temperature
Molecular Formula
– C34H40N8O9
References
– [1]Etersque JM et al. Regulation of eDHFR-tagged proteins with trimethoprim PROTACs. Nat Commun. 2023 Nov 3;14(1):7071.
Molecular Weight
– 704.73
SMILES
– NC1=C(CC2=CC(OC)=C(OCCCC(NCCOCCNC3=C(C(N(C4C(NC(CC4)=O)=O)C5=O)=O)C5=CC=C3)=O)C(OC)=C2)C=NC(N)=N1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Bacterial;PROTACs
Pathway
– Anti-infection;PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
