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PROTAC Bcl-xL ligand-1
$500 – $4,650
Products Details
Product Description
– PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs[1].
Web ID
– HY-139304
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H29IN4O4S2
References
– [1]Chun-Wa Chung, et al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.
Molecular Weight
– 724.63
Compound Purity
– 90.
SMILES
– O=C(C1=C(CCCOC2=CC=C(I)C=C2)SC(N3CCC4=C(C(C(NC5=NC6=CC=CC=C6S5)=O)=CC=C4)C3)=N1)OCC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family;Ligands for Target Protein for PROTAC
Pathway
– Apoptosis;PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
