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Prostaglandin E2-d4
$257
Products Details
Product Description
– Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2].
Web ID
– HY-101952S
Shipping
– Room temperature
Molecular Formula
– C20H28D4O5
References
– [1]Chouaib S, et al. The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol. 1984 Apr;132(4):1851-7.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[3]Fernandez-Repollet E, et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70.|[4]Haylor J, et al. Renal vasodilator activity of prostaglandin E2 in the rat anaesthetized with pentobarbitone. Br J Pharmacol. 1982 May;76(1):131-7.
CAS Number
– 34210-10-1
Molecular Weight
– 356.49
SMILES
– OC(CC([2H])([2H])C([2H])([2H])/C=CC[C@@H](C(C1)=O)[C@H]([C@@H]1O)/C=C/[C@@H](O)CCCCC)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
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