Download Files:
Products Details
Product Description
– Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity.
Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer’s disease or vascular dementia.
Web ID
– HY-107203
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H22N4O3
References
– [1]Hudlicka O, Komarek J, Wright AJ. The effect of a xanthine derivative, 1-(5′ oxohexyl)-3-methyl-7-propylxanthine (HWA 285), on heart performance and regional blood flow in dogs and rabbits. Br J Pharmacol. 1981;72(4):723-730. |[2]Sweitzer S, De Leo J. Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain. Handb Exp Pharmacol. 2011;(200):235-250.
CAS Number
– 55242-55-2
Molecular Weight
– 306.36
SMILES
– O=C1C2=C(N(C)C(N1CCCCC(C)=O)=O)N=CN2CCC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
