Download Files:
Propargyl-PEG8-NH2
$25 – $140
Products Details
Product Description
– Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-130182
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H37NO8
References
– [1]Genady AR, et al. Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That TargetProstate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy. J Med Chem. 2016 Mar 24;59(6):2660-73.
CAS Number
– 1196732-52-1
Molecular Weight
– 407.50
Compound Purity
– 98.0
SMILES
– C#CCOCCOCCOCCOCCOCCOCCOCCOCCN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Non-cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
