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Promegestone
$650 – $3,100
Products Details
Product Description
– Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research[1].
Web ID
– HY-119384
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C22H30O2
References
– [1]Clémentine Garoche, et al. Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins. Environ Sci Technol. 2020 Aug 4;54(15):9510-9518.|[2]Michael A Kirby, et al. Progesterone Receptor-Mediated Actions Regulate Remodeling of the Cervix in Preparation for Preterm Parturition. Reprod Sci. 2016 Nov;23(11):1473-1483.|[3]Todd P Knutson, et al. Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs. J Hematol Oncol. 2017 Apr 17;10(1):89.
CAS Number
– 34184-77-5
Molecular Weight
– 326.47
Compound Purity
– 98.0
SMILES
– C[C@@]12[C@](C)(CC[C@]1([C@@]3(CCC4=CC(CCC4=C3CC2)=O)[H])[H])C(CC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Progesterone Receptor
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
