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Products Details
Product Description
– Prohibitin ligand 1 (Compound 22i), a cardioprotectant prohibitin ligand, induces a phosphorylation of the pro-survival factor STAT3. Prohibitin ligand 1 exhibits in vitro cardioprotectant activities at nanomolar concentrations[1].
Web ID
– HY-146441
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H22N2O
References
– [1]Sabria Elderwish, et al. Discovery of 3,3′-pyrrolidinyl-spirooxindoles as cardioprotectant prohibitin ligands. Eur J Med Chem. 2020 Jan 15;186:111859.
Molecular Weight
– 306.40
SMILES
– CC(N1CC[C@]2([C@@H]1C3=CC=CC=C3)C(NC4=CC=CC=C42)=O)C
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– STAT
Pathway
– JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
