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Products Details
Product Description
– PRMT5-IN-27 (compound 481) is an inhibitor of PRMT5. PRMT5-IN-27 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].
Web ID
– HY-153390
Shipping
– Room temperature
Molecular Formula
– C22H19F3N4O3
References
– [1]Shon Booker, et al. Prmts inhibitors. WO2022132914A1. 2022-06-23.
CAS Number
– 2790567-82-5
Molecular Weight
– 444.41
SMILES
– O=C(N1[C@@H](C2=CC=C(C=C2)C(F)(F)F)COCC1)C3=NC=C4N=C(N)C(COC5)=C5C4=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
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