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PRMT5-IN-15
SKU
HY-142211-Get quote
Category Reference compound
Tags Cancer, Epigenetics, Histone Methyltransferase
Products Details
Product Description
– PRMT5-IN-15 is a PRMT5 inhibitor with an IC50 value of 0.84 nM.
Web ID
– HY-142211
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H23F3N6O2
References
– [1]Quiroz RV, et al. The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. J Med Chem. 2021 Apr 8;64(7):3911-3939.
CAS Number
– 2410637-87-3
Molecular Weight
– 484.47
SMILES
– NC1=NC2=CC(C[C@@H]3CC[C@@]4([C@H]([C@@H](C[C@H]34)N5C=C(C6=C5N=CN=C6N)F)O)O)=CC(F)=C2C=C1F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– PRMT5
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.