Products Details

Product Description

– PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.

Web ID

– HY-139823A

Shipping

– Room temperature

Molecular Formula

– C13H17N5O4

References

– [1]Jouffroy L, et al. Regio- and Stereoselective Synthesis of C-4′ Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues. Org Lett. 2021 Nov 19;23(22):8828-8833.

CAS Number

– 2567564-33-2

Molecular Weight

– 307.31

SMILES

– OC[C@@H]1[C@@]([C@H]2O)(CC1)O[C@](N3C4=NC=NC(N)=C4N=C3)([H])[C@@H]2O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– Histone Methyltransferase

Isoform

– PRMT5

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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